Description

Pyridine, 2-Fluoro-5-[[(2S)-1-Methyl-2-Azetidinyl]Methoxy]- (9Ci) CAS NO 209327-88-8 is a high-purity, structurally complex heterocyclic compound featuring a pyridine core substituted with a fluorinated azetidine moiety. This compound is of significant value as a key chiral intermediate or building block in advanced organic synthesis, enabling the development of novel molecular architectures. It is primarily sought after by pharmaceutical research and development organizations and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the research and synthesis of novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.
• Active Pharmaceutical Ingredient (API) Development: Used in the development and scale-up processes for new APIs requiring a specific fluorinated azetidine-pyridine pharmacophore.
• Agrochemical Research: Acts as a specialty intermediate in the discovery and synthesis of new generation pesticides and herbicides.
• Ligand and Catalyst Synthesis: Employed in the preparation of complex ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science Research: Utilized as a monomer or functional additive in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Used to create molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	Pyridine, 2-Fluoro-5-[[(2S)-1-Methyl-2-Azetidinyl]Methoxy]- (9Ci)
CAS No.	209327-88-8
Molecular Formula	C10H13FN2O
Molecular Weight	196.22 g/mol
Synonyms	2-Fluoro-5-[[(2S)-1-Methyl-2-azetidinyl]methoxy]pyridine; (S)-2-Fluoro-5-((1-methylazetidin-2-yl)methoxy)pyridine; 2-Fluoro-5-[(1-methyl-2-azetidinyl)methoxy]pyridine, (2S)-; 209327-88-8; (S)-2-Fluoro-5-((1-methylazetidin-2-yl)methoxy)pyridine; 2-Fluoro-5-(((2S)-1-methylazetidin-2-yl)methoxy)pyridine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and chiral integrity. Certificates of Analysis (COA) are provided, detailing results from HPLC, NMR, and chiral purity analysis. We support cGMP compliance for pharmaceutical applications, with documentation tailored to meet the stringent requirements of R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.