Description

Okadaic Acid Sodium Salt is a highly specific and potent inhibitor of protein phosphatases PP1 and PP2A. This compound is a critical biochemical tool for studying cellular signaling pathways, particularly those involving protein phosphorylation and dephosphorylation. It is essential for researchers and manufacturers in the fields of molecular biology, toxicology, and pharmaceutical development who require a reliable, high-purity reagent for mechanistic studies and assay development.

Application

• Biochemical Research: A primary tool for investigating signal transduction, cell cycle regulation, and apoptosis by selectively inhibiting serine/threonine protein phosphatases.
• Toxicology Studies: Used as a reference standard and active agent in studies of diarrhetic shellfish poisoning (DSP) and marine biotoxins.
• Pharmaceutical Screening: Employed in high-throughput screening assays to identify novel compounds that modulate phosphatase activity for therapeutic discovery.
• Cell Biology: Induces hyperphosphorylation of proteins in cell culture models to study the functional consequences in metabolism, gene expression, and cytoskeletal organization.
• Diagnostic Development: Serves as a key component in the development and calibration of immunoassays and analytical methods for detecting okadaic acid and related toxins in food safety testing.

Basic Information

Product Name	Okadaic Acid Sodium Salt
CAS No.	209266-80-8
Molecular Formula	C44H65NaO13
Molecular Weight	824.97 g/mol
Synonyms	Okadaic Acid Na Salt; Sodium Okadaate; 9,10-Deepithio-9,10-didehydroacanthifolicin Sodium Salt; OA Sodium Salt; NSC 332007; PP1/PP2A Inhibitor (Okadaic Acid, Sodium Salt); Acanthifolicin congener sodium salt
EINECS	Contact for details

Quality Control

Our Okadaic Acid Sodium Salt is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for biochemical reagents, ensuring suitability for sensitive cell-based and enzymatic assays.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Assay (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.