Description

Mmp-3 Inhibitor Viii CAS NO 208663-26-7 is a potent and selective small molecule inhibitor of matrix metalloproteinase-3 (MMP-3), also known as stromelysin-1. This compound is a critical research tool for investigating the role of MMP-3 in extracellular matrix remodeling, inflammatory processes, and associated disease pathways. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel therapeutics for conditions such as arthritis, cancer metastasis, and cardiovascular diseases.

Application

• Biochemical Research: A key reagent for in vitro enzymatic assays to study MMP-3 kinetics, inhibition mechanisms, and substrate specificity.
• Drug Discovery & Development: Used as a reference standard and pharmacological tool in high-throughput screening (HTS) and lead optimization programs targeting MMP-3.
• Disease Mechanism Studies: Enables investigation into the pathological role of MMP-3 in rheumatoid arthritis, osteoarthritis, atherosclerosis, and tumor progression.
• Cell Culture & In Vitro Models: Applied in cell-based assays to modulate MMP-3 activity and study its effects on cell migration, invasion, and signaling pathways.
• Proteomics & Molecular Biology: Used to selectively inhibit MMP-3 in complex biological samples to identify its specific substrates and proteolytic footprint.

Basic Information

Item	Details
Product Name	Mmp-3 Inhibitor Viii
CAS No.	208663-26-7
Molecular Formula	C₁₉H₁₈N₄O₃
Molecular Weight	350.37 g/mol
Synonyms	MMP-3 Inhibitor VIII; N-Isobutyl-N-[4-methoxyphenylsulfonyl]glycyl hydroxamic acid; MMP-3 Inhibitor, Selective; Isobutylmethoxyhenylsulfonyl Glycine Hydroxamate; CAS 208663-26-7; MMP3 Inhibitor; Stromelysin-1 Inhibitor
EINECS	Contact for details

Quality Control

Our Mmp-3 Inhibitor Viii is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment, NMR and MS for structural confirmation, and functional activity testing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and assay results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.