Description

2,3-Dihydrobenzo[B]Thiophene-6-Sulfonyl Chloride 1,1-Dioxide (Wx142546) is a high-purity, reactive sulfonyl chloride derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile electrophilic reagent, enabling the efficient introduction of the sulfonamide functional group under controlled conditions. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in creating sulfonamide-based molecules with potential therapeutic or pesticidal activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) containing sulfonamide moieties, which are prevalent in various drug classes.
• Agrochemical Synthesis: Used in the research and production of modern herbicides, fungicides, and insecticides that utilize sulfonamide chemistry for enhanced efficacy.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced functional materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes to study biological systems.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and pigments, particularly sulfonated colorants.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic routes.

Basic Information

Product Name	2,3-Dihydrobenzo[B]Thiophene-6-Sulfonyl Chloride 1,1-Dioxide (Wx142546)
CAS No.	208643-45-2
Molecular Formula	C8H7ClO4S2
Molecular Weight	266.72 g/mol
Synonyms	2,3-Dihydrobenzo[b]thiophene-6-sulfonyl chloride 1,1-dioxide; 2,3-Dihydro-1-benzothiophene-6-sulfonyl chloride 1,1-dioxide; 6-(Chlorosulfonyl)-2,3-dihydro-1-benzothiophene 1,1-dioxide; 2,3-Dihydrobenzo[b]thiophene-6-sulfonyl chloride S,S-dioxide; Wx142546; 208643-45-2; Dihydrobenzothiophene sulfonyl chloride dioxide
EINECS	Contact for details

Quality Control

Our 2,3-Dihydrobenzo[B]Thiophene-6-Sulfonyl Chloride 1,1-Dioxide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes rigorous analytical testing, including HPLC for assay and impurity profiling, to meet exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.