Description

Ganirelix 1-4 Peptide is a high-purity synthetic peptide fragment derived from the gonadotropin-releasing hormone (GnRH) antagonist, Ganirelix. This compound is critical for advanced pharmaceutical research and development, particularly in the study of reproductive endocrinology and the development of therapeutic analogs. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on peptide-based drug discovery and process development.

Application

• Pharmaceutical Reference Standard: Serves as a critical analytical standard for the quality control and validation of Ganirelix Acetate API and related drug products.
• Biochemical Research: Used in structure-activity relationship (SAR) studies to understand the binding affinity and antagonistic activity of GnRH receptor ligands.
• Process Development: Acts as a key intermediate or building block in the synthetic pathway for developing novel GnRH antagonist peptides.
• Analytical Method Development: Employed in the development and calibration of HPLC, LC-MS, and other chromatographic methods for peptide analysis.
• Peptide Library Synthesis: Utilized as a precursor for creating specialized peptide libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	Ganirelix 1-4 Peptide
CAS No.	208599-57-9
Molecular Formula	C₁₀₀H₁₄₈N₂₈O₂₀
Molecular Weight	2150.4 g/mol
Synonyms	Ganirelix Fragment 1-4; Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-NH2; [Ac-D-2-Nal1, D-4-Cpa2, D-3-Pal3, Ser4]-GnRH (1-4); Ganirelix (1-4) tetrapeptide; GnRH Antagonist Fragment (1-4); Antide-related peptide fragment; Ac-2-Nal-4-Cl-Phe-3-Pal-Ser-NH2
EINECS	Contact for details

Quality Control

Our Ganirelix 1-4 Peptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral purity analysis. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.