Description

2-Pyridinecarboxaldehyde, 6-(Difluoromethyl)- (9Ci) is a specialized pyridine derivative featuring a difluoromethyl substituent, serving as a high-value building block in advanced organic synthesis. This compound is prized for its unique reactivity, enabling the introduction of both aldehyde and difluoromethyl functional groups into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the difluoromethyl group can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials with tailored properties.
• Fluorine Chemistry Studies: An important reagent for investigating the effects of fluorine substitution on chemical reactivity and physical properties in heterocyclic systems.

Basic Information

Product Name	2-Pyridinecarboxaldehyde, 6-(Difluoromethyl)- (9Ci)
CAS No.	208111-30-2
Molecular Formula	C7H5F2NO
Molecular Weight	157.12 g/mol
Synonyms	6-(Difluoromethyl)pyridine-2-carboxaldehyde; 6-(Difluoromethyl)-2-pyridinecarboxaldehyde; 2-Pyridinecarboxaldehyde, 6-(difluoromethyl)-; 6-(Difluoromethyl)picolinaldehyde; 2-Formyl-6-(difluoromethyl)pyridine; 6-Difluoromethyl-pyridine-2-carbaldehyde
EINECS	Contact for details

Quality Control

Our production of 2-Pyridinecarboxaldehyde, 6-(Difluoromethyl)- adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (HPLC, GC, NMR) are provided to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.