Description

2-Fluoro-6-Formylpyridine is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a formyl group and a fluorine atom on the pyridine ring, makes it an indispensable precursor for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create fluorescent tags and molecular probes for studying biological processes.
• Cross-Coupling Reactions: The formyl group and halogenated ring make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Item	Details
Product Name	2-Fluoro-6-Formylpyridine
CAS No.	208110-81-0
Molecular Formula	C6H4FNO
Molecular Weight	125.10 g/mol
Synonyms	6-Fluoro-2-pyridinecarboxaldehyde; 2-Fluoro-6-pyridinecarboxaldehyde; 2-Fluoropyridine-6-carboxaldehyde; 6-Fluoropyridine-2-carbaldehyde; 2-Fluoro-6-pyridylcarboxaldehyde; 6-Fluoro-2-formylpyridine; 2-Fluoropyridine-6-carbaldehyde; 6-Fluoropicolinaldehyde
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Formylpyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, GC, and NMR spectra, to verify identity and purity. Certificates of Analysis (COA) are available for every batch and supplied upon request, ensuring full transparency and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.