Description

5-Chloro-3-Fluoropyridine-2-Carboxylic Acid is a high-purity, multifunctional heterocyclic building block essential for advanced organic synthesis. Its value lies in its unique halogenated pyridine core, which serves as a critical precursor for constructing complex molecules with tailored biological and physical properties. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of modern herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis services catering to R&D and pilot-scale production.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in regulatory and research laboratories.

Basic Information

Product Name	5-Chloro-3-Fluoropyridine-2-Carboxylic Acid
CAS No.	207994-08-9
Molecular Formula	C6H3ClFNO2
Molecular Weight	175.54 g/mol
Synonyms	2-Carboxy-5-chloro-3-fluoropyridine; 5-Chloro-3-fluoro-2-pyridinecarboxylic acid; 5-Chloro-3-fluoropicolinic acid; 3-Fluoro-5-chloropyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 5-chloro-3-fluoro-; Picolinic acid, 5-chloro-3-fluoro-; 207994-08-9; 5-Chloro-3-fluoropyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-Fluoropyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its acidic nature, ensure storage containers are compatible with strong acids/organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.