Description

Ethyl 3-Fluoro-5-(Trifluoromethyl)Picolinate is a high-purity fluorinated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in enabling the precise construction of complex molecules, particularly in the development of novel active ingredients. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Crucial precursor in the development of next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the creation of novel fluorinated organic materials, including liquid crystals and electronic chemicals.
• Chemical Biology: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for bespoke synthesis projects requiring high-value fluorinated intermediates.

Basic Information

Product Name	Ethyl 3-Fluoro-5-(Trifluoromethyl)Picolinate
CAS No.	207994-07-8
Molecular Formula	C9H7F4NO2
Molecular Weight	237.15 g/mol
Synonyms	Ethyl 3-Fluoro-5-(trifluoromethyl)pyridine-2-carboxylate; 2-Pyridinecarboxylic acid, 3-fluoro-5-(trifluoromethyl)-, ethyl ester; 3-Fluoro-5-(trifluoromethyl)picolinic acid ethyl ester; Ethyl 3-fluoro-5-trifluoromethylpicolinate; 207994-07-8; Ethyl 3-Fluoro-5-(trifluoromethyl)-2-pyridinecarboxylate; 5-(Trifluoromethyl)-3-fluoropicolinic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-Fluoro-5-(Trifluoromethyl)Picolinate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.