Description

4-Bromo-2-(Trifluoromethyl)Phenyl Isothiocyanate is a specialized aromatic isothiocyanate derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both bromo and trifluoromethyl substituents, provides unique reactivity and physicochemical properties for constructing complex molecules. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Used to create specialized ligands for metal complexes and catalysts in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, or organic electronic materials due to its functional groups.
• Chemical Biology Probes: Useful for synthesizing activity-based probes (ABPs) to study enzyme function and mechanism.
• Custom Synthesis and R&D: Serves as a versatile starting material for contract research organizations and fine chemical manufacturers.

Basic Information

Product Name	4-Bromo-2-(Trifluoromethyl)Phenyl Isothiocyanate
CAS No.	206559-46-8
Molecular Formula	C8H3BrF3NS
Molecular Weight	282.08 g/mol
Synonyms	1-Bromo-4-isothiocyanato-2-(trifluoromethyl)benzene; 2-(Trifluoromethyl)-4-bromophenyl isothiocyanate; 4-Bromo-α,α,α-trifluoro-o-tolyl isothiocyanate; (4-Bromo-2-(trifluoromethyl)phenyl) isothiocyanate; Isothiocyanic acid, 4-bromo-2-(trifluoromethyl)phenyl ester; CAS 206559-46-8
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-(Trifluoromethyl)Phenyl Isothiocyanate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed under an inert atmosphere if possible to maximize shelf-life stability. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, oxidizing agents, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.