Description

Cloprostenol is a synthetic prostaglandin analog, a potent and highly specific luteolytic agent. This compound is critical for precise reproductive cycle management in livestock, offering significant value in improving breeding efficiency and herd health. It is primarily utilized by professionals in the veterinary pharmaceutical and animal husbandry industries for estrus synchronization and the treatment of reproductive disorders. Cloprostenol CAS NO 206555-98-8 represents a key active pharmaceutical ingredient (API) for manufacturing advanced veterinary therapeutics.

Application

• Veterinary Pharmaceutical API: Primary active ingredient in injectable solutions for estrus synchronization in cattle, horses, and swine.
• Estrus Synchronization Programs: Enables timed artificial insemination (TAI) to improve reproductive efficiency and management in dairy and beef herds.
• Treatment of Reproductive Disorders: Used for inducing luteolysis to treat conditions like pyometra (chronic endometritis) and mummified fetus.
• Parturition Induction: Assists in the controlled induction of labor in livestock when necessary for animal welfare.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological and veterinary research.
• Veterinary Formulation Development: Used by manufacturers developing new generics or proprietary reproductive health products.

Basic Information

Product Name	Cloprostenol
CAS No.	206555-98-8
Molecular Formula	C22H29ClO6
Molecular Weight	424.91 g/mol
Synonyms	Cloprostenol Sodium; ICI 80996; Estrumate; Planate; (+)-Cloprostenol; (5Z)-7-[(1R,2R,3R,5S)-2-[(E)-4-(3-Chlorophenoxy)-3-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid; 2-[(E)-4-(3-Chlorophenoxy)-3-butenyl]-3,5-dihydroxycyclopentyl]-5-heptenoic Acid
EINECS	Contact for details

Quality Control

Our Cloprostenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and potency meet exacting standards suitable for pharmaceutical use. Certificates of Analysis (COA) are provided, detailing results from tests including assay, related substances, residual solvents, and specific rotation. We adhere to cGMP principles to ensure supply reliability and batch-to-batch consistency for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation	+48° to +52° (c=1 in ethanol)
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.