Description

Methyl 2-Methyl-6-(Trifluoromethyl)Nicotinate is a high-purity, synthetically valuable trifluoromethylated pyridine derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the development of novel agrochemicals and fine chemicals. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for synthesizing compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral drugs.
• Agrochemical Synthesis: Used as a building block for developing new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and biological efficacy.
• Material Science Research: Employed in the creation of specialty chemicals, liquid crystals, and organic electronic materials due to its unique electronic properties imparted by the fluorine atoms.
• Chemical Biology & Medicinal Chemistry: Serves as a probe or precursor in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	Methyl 2-Methyl-6-(Trifluoromethyl)Nicotinate
CAS No.	205582-88-3
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	Methyl 2-methyl-6-(trifluoromethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-methyl-6-(trifluoromethyl)-, methyl ester; 6-(Trifluoromethyl)-2-picolinic acid methyl ester; 2-Methyl-6-trifluoromethylnicotinic acid methyl ester; Methyl 6-(trifluoromethyl)-2-picolinate; 2-Methyl-6-(trifluoromethyl)nicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Methyl-6-(Trifluoromethyl)Nicotinate adheres to strict in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Quality is verified against established internal specifications using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.