Description

2-Chloro-4-Iodo-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative. This compound serves as a critical building block in advanced organic synthesis, prized for its unique reactivity profile imparted by the chlorine, iodine, and trifluoromethyl substituents. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyridine core.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: The iodine and chlorine atoms make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to build complex molecular architectures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Chloro-4-Iodo-6-(Trifluoromethyl)Pyridine
CAS No.	205444-22-0
Molecular Formula	C6H2ClF3IN
Molecular Weight	321.44 g/mol
Synonyms	2-Chloro-4-iodo-6-(trifluoromethyl)pyridine; 4-Iodo-2-chloro-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-2-chloro-4-iodopyridine; Pyridine, 2-chloro-4-iodo-6-(trifluoromethyl)-; 2-Chloro-4-iodo-6-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Iodo-6-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.