Description

2-Ah-Cgmp Sodium Salt is a high-purity biochemical reagent and a key derivative of cyclic guanosine monophosphate (cGMP). This compound is essential for advanced research in cellular signaling pathways, particularly those involving nitric oxide (NO) and protein kinase G (PKG) activation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers for developing novel therapeutics and conducting critical biochemical assays.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the development of cardiovascular and neurological drugs.
• Cell Signaling & Biochemistry Studies: Used as a potent and specific activator of protein kinase G (PKG) to study vasodilation, platelet aggregation, and neuronal function in vitro.
• Diagnostic Kit Manufacturing: Employed as a calibrated component in enzyme immunoassays (EIAs) and other diagnostic kits for measuring cGMP levels in biological samples.
• Academic & Institutional Research: A fundamental tool for investigating the role of the NO/cGMP pathway in various physiological and pathological processes.
• Preclinical Studies: Utilized in animal models to explore therapeutic potentials for conditions like hypertension, pulmonary arterial hypertension, and erectile dysfunction.

Basic Information

Product Name	2-Ah-Cgmp Sodium Salt
CAS No.	205368-58-7
Molecular Formula	C20H23N6Na2O13P2 (or similar, contact for exact)
Molecular Weight	Contact for details
Synonyms	2-AHCGMP Sodium Salt; 2-Arylhydrazinocytidine cyclic GMP Sodium Salt; 8-(2-Aminophenylhydrazino)-cGMP Sodium Salt; cGMP Derivative Sodium Salt; 2-Ah-8-(2-aminophenylhydrazino)-guanosine 3',5'-cyclic monophosphate sodium salt; Protein Kinase G Activator; PKG Activator; Cyclic GMP Analog Sodium Salt
EINECS	Contact for details

Quality Control

Our 2-Ah-Cgmp Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 90% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.