Description

Tubulysin C is a highly potent, naturally occurring cytotoxic peptide that belongs to the tubulysin family of microtubule-destabilizing agents. Its exceptional potency makes it a critical compound for advanced research in oncology and drug discovery. This product is essential for pharmaceutical R&D teams, medicinal chemists, and academic researchers focused on developing next-generation antibody-drug conjugates (ADCs) and targeted cancer therapies.

Application

• Antibody-Drug Conjugate (ADC) Payload: Serves as a highly potent warhead in the development of novel ADCs targeting specific cancer cell receptors.
• Cancer Research & Drug Discovery: Used as a reference standard and active pharmaceutical ingredient (API) in preclinical studies to investigate mechanisms of microtubule inhibition and apoptosis.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) research to design and synthesize novel analogs with improved therapeutic indices.
• Biochemical Research: A valuable tool for studying cell cycle dynamics, cytoskeleton disruption, and mechanisms of action of cytotoxic agents in vitro.

Basic Information

Product Name	Tubulysin C
CAS No.	205304-88-7
Molecular Formula	C₄₃H₆₅N₅O₁₀S
Molecular Weight	844.07 g/mol
Synonyms	Tubulysin C; Tubugis C; (2S,4R)-4-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-5-[(2S,5S,8S,11S)-5,8-diisopropyl-11-methyl-2-(2-methyl-1,3-thiazol-4-yl)-4,7,10-trioxo-3,6,9,12-tetraazatetradecan-14-oyl]amino]-5-oxopentanoic acid
EINECS	Contact for details

Quality Control

Our Tubulysin C is manufactured under strict quality management systems to ensure the highest standards of purity and consistency required for pharmaceutical research. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines for the production of advanced pharmaceutical intermediates, ensuring reliable and reproducible performance in your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, inert environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep desiccated under an inert atmosphere such as argon or nitrogen. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.