Description

L-Cysteine-n-T-Boc, S-p-Mebz (15N) is a specifically labeled, protected derivative of the amino acid cysteine, featuring a tert-butoxycarbonyl (Boc) group on the nitrogen and a p-methylbenzyl (p-Mebz) group on the sulfur, with a 15N isotope label. This compound is critical for advanced research and development, providing a stable, isotopically enriched building block for precise structural elucidation and metabolic studies. It is primarily utilized by pharmaceutical researchers, isotope labeling specialists, and chemical manufacturers involved in peptide synthesis and proteomics.

Application

• Isotope-Labeled Peptide Synthesis: As a key 15N-labeled intermediate for the solid-phase or solution-phase synthesis of isotopically enriched peptides for NMR spectroscopy and mass spectrometry studies.
• Proteomics & Metabolic Research: Used in quantitative proteomics and metabolic pathway tracing to study protein turnover, interactions, and degradation mechanisms.
• Pharmaceutical R&D: Serves as a protected precursor in the development of novel drug candidates, particularly those targeting cysteine proteases or requiring disulfide bond formation.
• Bioconjugation & Chemical Biology: The protected thiol group allows for site-specific modifications and conjugation strategies in the design of biochemical probes and labeled biomolecules.
• Reference Standard Production: Employed in the preparation of high-purity certified reference standards for analytical method development and validation in regulatory environments.

Basic Information

Product Name	L-Cysteine-n-T-Boc, S-p-Mebz (15N)
CAS No.	204523-23-9
Molecular Formula	C16H2315N O4S
Molecular Weight	Contact for details
Synonyms	(2R)-2-[(tert-Butoxycarbonyl)amino]-3-[(4-methylbenzyl)sulfanyl]propanoic-15N acid; N-Boc-S-(4-Methylbenzyl)-L-cysteine-15N; Nα-(tert-Butoxycarbonyl)-S-(p-methylbenzyl)-L-cysteine-15N; Boc-Cys(p-MeBzl)-OH-15N; L-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-, S-[(4-methylphenyl)methyl] ester, (15N)-; N-Boc-S-p-Methylbenzyl-L-cysteine-15N; Boc-Cys(4-MeBzl)-OH-15N
EINECS	Contact for details

Quality Control

Our L-Cysteine-n-T-Boc, S-p-Mebz (15N) is manufactured under strict quality systems to ensure high isotopic and chemical purity for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation. We adhere to cGMP principles where applicable to support its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (15N)	≥ 98 atom %
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.