Description

Mmp-9/Mmp-13 Inhibitor I is a potent, cell-permeable, and selective inhibitor of matrix metalloproteinases 9 and 13 (MMP-9 and MMP-13). This compound is crucial for researchers investigating the role of these enzymes in pathological tissue remodeling, inflammation, and cancer metastasis. It is an essential biochemical tool for pharmaceutical R&D, academic research, and preclinical studies focused on developing novel therapeutics for osteoarthritis, rheumatoid arthritis, and various cancers.

Application

• Biochemical Research: A key tool for in vitro enzymatic assays to study the inhibition kinetics and specificity of MMP-9 and MMP-13.
• Cell-Based Studies: Used in cell culture models to investigate the role of MMP-9/13 in cellular invasion, migration, and extracellular matrix degradation.
• Drug Discovery & Development: Serves as a reference compound and pharmacological probe in high-throughput screening and lead optimization programs targeting MMPs.
• Disease Mechanism Research: Facilitates the study of MMP-9/13 involvement in osteoarthritis, rheumatoid arthritis, atherosclerosis, and tumor progression.
• Preclinical Animal Studies: Employed in animal models of disease to validate MMP-9 and MMP-13 as therapeutic targets and assess efficacy of novel inhibitors.

Basic Information

Product Name	Mmp-9/Mmp-13 Inhibitor I
CAS No.	204140-01-2
Molecular Formula	C₂₀H₂₀N₄O₃S
Molecular Weight	396.46 g/mol
Synonyms	N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-[(4-(4-pyridinyl)phenyl)carbonyl]piperazine-2-carboxamide; MMP-9/13 Inhibitor I; CAS 204140-01-2; MMP-9 Inhibitor II; MMP-13 Inhibitor; MMP-9/MMP-13 Inhibitor; (4-Pyridin-4-yl-phenyl)-[4-(toluene-4-sulfonyl)-3-(hydroxycarbamoyl)-piperazin-1-yl]-methanone
EINECS	Contact for details

Quality Control

Our Mmp-9/Mmp-13 Inhibitor I is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and functional activity testing. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. The product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.