Description

2,4-Dichloro-3-Nitrobenzotrifluoride is a versatile halogenated nitroaromatic compound featuring a trifluoromethyl group, making it a valuable building block in advanced chemical synthesis. Its unique structure provides a reactive scaffold for the development of complex molecules, particularly in the agrochemical and pharmaceutical sectors. This intermediate is essential for manufacturers and R&D chemists involved in creating active ingredients, dyes, and functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the reactivity of its nitro and chloro substituents.
• Pharmaceutical Building Block: Used in the research and development of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Dye and Pigment Synthesis: Serves as an intermediate in the production of specialized dyes and pigments, where the trifluoromethyl group can alter color properties and light fastness.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and electronic materials that incorporate fluorinated aromatic units.
• Cross-Coupling Reactions: An effective substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl structures.
• Nucleophilic Aromatic Substitution: The activated chloro and nitro groups make it suitable for reactions with amines, alkoxides, and other nucleophiles.

Basic Information

Product Name	2,4-Dichloro-3-Nitrobenzotrifluoride
CAS No.	203915-49-5
Molecular Formula	C7H2Cl2F3NO2
Molecular Weight	264.00 g/mol
Synonyms	1,2-Dichloro-4-nitro-5-(trifluoromethyl)benzene; 3-Nitro-2,4-dichlorobenzotrifluoride; 2,4-Dichloro-3-nitro-α,α,α-trifluorotoluene; Benzene, 1,2-dichloro-4-nitro-5-(trifluoromethyl)-; 5-(Trifluoromethyl)-2,4-dichloronitrobenzene
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-3-Nitrobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Ensure the container is kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.