Description

3-Chloro-2-Iodobenzotrifluoride is a versatile halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring chlorine, iodine, and a trifluoromethyl group on a benzene ring, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the introduction of fluorine and halogen atoms can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for advanced organic materials, including liquid crystals, organic semiconductors, and polymers with specific optical or electronic properties.
• Chemical Synthesis Reagent: Employed in organic synthesis laboratories for the selective functionalization of aromatic systems and as a scaffold for discovering new chemical entities.
• Ligand and Catalyst Development: Useful for synthesizing specialized ligands for metal catalysis or as a core structure in catalyst design.

Basic Information

Product Name	3-Chloro-2-Iodobenzotrifluoride
CAS No.	203626-41-9
Molecular Formula	C7H3ClF3I
Molecular Weight	305.45 g/mol
Synonyms	2-Iodo-3-chlorobenzotrifluoride; 1-Chloro-2-iodo-3-(trifluoromethyl)benzene; 3-Chloro-2-iodo-α,α,α-trifluorotoluene; 3-Chloro-2-iodobenzotrifluoride; Benzene, 1-chloro-2-iodo-3-(trifluoromethyl)-; 2-Iodo-3-chloro-α,α,α-trifluorotoluene
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Iodobenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.