Description

3-Bromo-2-Chloro-6-Fluorotoluene is a halogenated toluene derivative that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and the construction of complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a specific halogenated aromatic core.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the halogen atoms can be modified or displaced to fine-tune biological activity.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Cross-Coupling Reactions: Serves as a valuable substrate in palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination for carbon-carbon and carbon-heteroatom bond formation.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Provides a multifunctional template for further derivatization in academic and industrial research settings.

Basic Information

Product Name	3-Bromo-2-Chloro-6-Fluorotoluene
CAS No.	203302-92-5
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-Bromo-2-chloro-3-fluoro-4-methylbenzene; 2-Chloro-3-fluoro-6-bromotoluene; 3-Bromo-2-chloro-6-fluoro-1-methylbenzene; Toluene, 3-bromo-2-chloro-6-fluoro-; 6-Fluoro-3-bromo-2-chlorotoluene; 2-Chloro-6-fluoro-3-bromotoluene; Benzene, 1-bromo-2-chloro-3-fluoro-4-methyl-
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Chloro-6-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Ensure the container is kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.