Description

6,8-Dioxabicyclo[3.2.1]Oct-3-Ene,2,2-Difluoro-,(1R)-(9Ci) is a high-value, chiral bicyclic ether building block containing fluorine atoms. This compound matters for its unique stereochemistry and fluorine substitution, which are critical for modulating the biological activity, metabolic stability, and physicochemical properties of advanced molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorine atoms and rigid bicyclic structure enhance efficacy and environmental profile.
• Fluorine Chemistry Research: Serves as a valuable substrate for studying novel fluorination reactions and the stereoselective construction of complex oxygen-containing heterocycles.
• Material Science Precursor: Potential use in the synthesis of specialized monomers for advanced polymers with tailored thermal and chemical resistance properties.
• Asymmetric Synthesis Building Block: Exploited for its fixed (1R) configuration to induce chirality in downstream synthetic pathways, ensuring high enantiomeric purity in final products.

Basic Information

Product Name	6,8-Dioxabicyclo[3.2.1]Oct-3-Ene,2,2-Difluoro-,(1R)-(9Ci)
CAS No.	203194-24-5
Molecular Formula	C6H6F2O2
Molecular Weight	148.11 g/mol
Synonyms	(1R)-2,2-Difluoro-6,8-dioxabicyclo[3.2.1]oct-3-ene; 2,2-Difluoro-6,8-dioxabicyclo[3.2.1]oct-3-ene, (1R)-; (1R)-2,2-Difluoro-6,8-dioxabicyclo[3.2.1]oct-3-ene (9CI); Bicyclo[3.2.1]oct-3-ene, 2,2-difluoro-6,8-dioxa-, (1R)-; 203194-24-5; (R)-2,2-Difluoro-6,8-dioxabicyclo[3.2.1]oct-3-ene
EINECS	Contact for details

Quality Control

Our production of 6,8-Dioxabicyclo[3.2.1]Oct-3-Ene,2,2-Difluoro-,(1R)-(9Ci) adheres to strict quality management protocols. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with research-grade and process development standards. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.