Description

1,2-Diiodo-4-Fluorobenzene is a halogenated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of iodine atoms, which serve as excellent handles for cross-coupling reactions, enabling the construction of complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a fluorinated diaryl structure.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, where the fluorine atom can enhance biological activity and stability.
• Material Science: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings due to the reactivity of the iodine substituents.
• Chemical Research: Employed in academic and industrial R&D labs for method development and exploring new reaction pathways in organofluorine chemistry.
• Ligand and Catalyst Preparation: Useful for synthesizing complex ligands and catalysts used in asymmetric synthesis and homogeneous catalysis.

Basic Information

Product Name	1,2-Diiodo-4-Fluorobenzene
CAS No.	203059-85-2
Molecular Formula	C6H3FI2
Molecular Weight	347.89 g/mol
Synonyms	4-Fluoro-1,2-diiodobenzene; 1,2-Diiodo-4-fluorobenzene; 4-Fluoro-o-diiodobenzene; Benzene, 1,2-diiodo-4-fluoro-; 3,4-Diiodofluorobenzene; o-Diiodo-4-fluorobenzene; 1-Fluoro-2,3-diiodobenzene
EINECS	Contact for details

Quality Control

Our 1,2-Diiodo-4-Fluorobenzene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.