Description

1-Bromo-3-Fluoro-5-Methylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of bromine and fluorine substituents on the benzene ring, which allows for selective functionalization and the introduction of unique physicochemical properties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed as a monomer or modifier to create specialty polymers with specific thermal, chemical, or optical properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromine moiety.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex molecular architectures.

Basic Information

Product Name	1-Bromo-3-Fluoro-5-Methylbenzene
CAS No.	202865-83-6
Molecular Formula	C7H6BrF
Molecular Weight	189.03 g/mol
Synonyms	3-Bromo-5-fluorotoluene; 5-Bromo-3-fluorotoluene; 3-Fluoro-5-bromotoluene; 1-Bromo-3-fluoro-5-methyl-benzene; Toluene, 3-bromo-5-fluoro-; 3-Bromo-5-methylfluorobenzene; 5-Fluoro-3-bromotoluene; Benzene, 1-bromo-3-fluoro-5-methyl-
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Fluoro-5-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.