Description

5-Bromo-2-Fluoro-4-Iodotoluene is a halogenated toluene derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and fungicides, leveraging its halogen-substituted aromatic structure.
• Material Science: Serves as a monomer or functionalizing agent in the production of specialty polymers and liquid crystal materials for electronic displays.
• Chemical Research: Employed in cross-coupling reactions (e.g., Suzuki, Stille) as a robust electrophilic coupling partner due to its bromo and iodo substituents.
• Ligand Preparation: Useful for synthesizing complex, multi-dentate ligands used in coordination chemistry and homogeneous catalysis.
• Fluorine Chemistry Studies: Acts as a model substrate for investigating the reactivity and effects of fluorine atoms in aromatic systems.

Basic Information

Product Name	5-Bromo-2-Fluoro-4-Iodotoluene
CAS No.	202865-75-6
Molecular Formula	C7H5BrFI
Molecular Weight	314.92 g/mol
Synonyms	1-Bromo-4-fluoro-2-iodo-5-methylbenzene; 2-Fluoro-5-bromo-4-iodotoluene; Toluene, 5-bromo-2-fluoro-4-iodo-; 4-Iodo-5-bromo-2-fluorotoluene; 5-Bromo-2-fluoro-1-iodo-4-methylbenzene; 2-Fluoro-4-iodo-5-bromotoluene
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoro-4-Iodotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting or in amber glass containers when possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.