Description

2-Fluoro-5-(Trifluoromethyl)Phenacyl Bromide 99% is a high-purity, multi-fluorinated organic bromide building block essential for advanced chemical synthesis. This compound matters because its unique structure, featuring both fluorine and bromine substituents, provides exceptional reactivity and serves as a versatile precursor for introducing complex fluorinated motifs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the preparation of novel herbicides and pesticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores in electronic and display materials.
• Cross-Coupling Reactions: The reactive phenacyl bromide moiety is valuable in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Fluorinated Ligand Development: Used to synthesize specialized ligands for catalysis and material science applications.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and fluorination chemistry.

Basic Information

Item	Details
Product Name	2-Fluoro-5-(Trifluoromethyl)Phenacyl Bromide
CAS No.	202664-36-6
Molecular Formula	C9H5BrF4O
Molecular Weight	261.04 g/mol
Synonyms	1-(2-Fluoro-5-(trifluoromethyl)phenyl)-2-bromoethan-1-one; 2'-Fluoro-5'-(trifluoromethyl)phenacyl bromide; α-Bromo-2-fluoro-5-(trifluoromethyl)acetophenone; 2-Bromo-1-[2-fluoro-5-(trifluoromethyl)phenyl]ethanone; Bromo(2-fluoro-5-(trifluoromethyl)phenyl)methanone; (2-Fluoro-5-trifluoromethylphenyl)bromoethanone
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-(Trifluoromethyl)Phenacyl Bromide 99% is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting or using amber glass containers where practical.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.