Description

Chloramphenicol (D5) is a deuterium-labeled internal standard of the broad-spectrum antibiotic Chloramphenicol, essential for precise quantitative analysis. This stable isotope-labeled compound is critical for ensuring accuracy and reliability in sensitive analytical methods, particularly in regulated environments. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities for applications in bioanalytical method development, pharmacokinetic studies, and residue testing.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the accurate measurement of Chloramphenicol in complex matrices.
• Pharmaceutical Metabolism Studies: Enables precise tracking and quantification of Chloramphenicol and its metabolites in pharmacokinetic and pharmacodynamic research.
• Veterinary Drug Residue Analysis: Critical for developing and validating methods to detect Chloramphenicol residues in food-producing animals, ensuring food safety compliance.
• Clinical Research & Toxicology: Supports bioanalytical assays in clinical trials and forensic toxicology for monitoring drug levels in biological fluids.
• Quality Control & Method Validation: Serves as a key component in the quality control protocols of pharmaceutical manufacturers and testing laboratories for assay validation.
• Environmental Monitoring: Applied in research methods aimed at detecting antibiotic contamination in environmental samples.

Basic Information

Product Name	Chloramphenicol (D5)
CAS No.	202480-68-0
Molecular Formula	C11H7D5Cl2N2O5
Molecular Weight	326.17 g/mol (for D5 isotopologue)
Synonyms	Chloramphenicol-d5; [D5]-Chloramphenicol; 2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide-d5; Chloromycetin-d5; Deuterated Chloramphenicol; Chloramphenicol (phenyl-d5); Internal Standard for Chloramphenicol
EINECS	Contact for details

Quality Control

Our Chloramphenicol (D5) is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, suitable for the most demanding analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and identity confirmation via advanced spectroscopic methods. We adhere to relevant standards for high-purity reference materials to support GMP, GLP, and ISO 17025 compliant laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, cool, and well-ventilated place. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D5)	≥ 98.0 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.