Description

L-Cysteine-13C3, 15N is a stable isotope-labeled analog of the essential amino acid L-Cysteine, where three carbon atoms and one nitrogen atom are replaced with their heavy isotopes. This compound is critical for advanced research requiring precise metabolic and proteomic pathway tracing. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications such as mass spectrometry-based quantification, drug metabolism studies, and biomarker discovery.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS/MS and GC-MS analyses for accurate measurement of endogenous cysteine levels in biological samples.
• Metabolic Flux Analysis: Enables the detailed tracing of sulfur amino acid metabolism in cell cultures, tissues, and whole organisms to study disease mechanisms and nutrient utilization.
• Proteomics and Protein Turnover Studies: Incorporated into proteins via cell culture (SILAC) or in vivo studies to measure protein synthesis and degradation rates.
• Pharmaceutical Research & Development: Employed in ADME (Absorption, Distribution, Metabolism, Excretion) studies to track the metabolic fate of drug candidates containing cysteine moieties.
• Nutritional Science Research: Investigates the bioavailability, metabolism, and physiological role of cysteine and its derivatives like glutathione.
• Diagnostic Assay Development: Serves as a key component in calibrating assays for clinical diagnostics related to oxidative stress and metabolic disorders.

Basic Information

Item	Detail
Product Name	L-Cysteine-13C3, 15N
CAS No.	202406-97-1
Molecular Formula	¹³C₃H₇NO₂S
Molecular Weight	Contact for details
Synonyms	(2R)-2-Amino-3-sulfanylpropanoic-¹³C₃,¹⁵N; L-Cysteine (³-¹³C, ¹⁵N); L-Cysteine-¹³C₃,¹⁵N; Cysteine-13C3,15N; (R)-2-Amino-3-mercaptopropionic-13C3,15N acid; Stable Isotope Labeled L-Cysteine; Cys-13C3,15N; Isotopic Cysteine
EINECS	Contact for details

Quality Control

Every batch of L-Cysteine-13C3, 15N is manufactured and tested under strict quality management systems to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on isotopic enrichment, chemical purity, and specific analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. The container must be kept tightly sealed in a desiccated environment after each use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % ¹³C; ≥ 99 atom % ¹⁵N
Chemical Purity (HPLC)	≥ 98.0%
Optical Rotation	Specific range available on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.