Description

4-Bromo-5-Chloro-2-Fluorotoluene is a halogenated toluene derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs), agrochemicals, and functional materials where its specific halogen substitution pattern enables precise molecular modifications.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic display technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitution reactions to introduce functionalized aromatic rings.
• Chemical Research & Development: Essential for academic and industrial research exploring new synthetic methodologies and novel compound libraries.
• Dye & Pigment Intermediate: Used in the synthesis of specialized halogenated dyes and pigments.

Basic Information

Product Name	4-Bromo-5-Chloro-2-Fluorotoluene
CAS No.	201849-17-4
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	2-Fluoro-4-bromo-5-chlorotoluene; 1-Bromo-2-chloro-5-fluoro-4-methylbenzene; Toluene, 4-bromo-5-chloro-2-fluoro-; 4-Bromo-5-chloro-2-fluoro-1-methylbenzene; 5-Chloro-4-bromo-2-fluorotoluene
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Chloro-2-Fluorotoluene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.