Description

1-Methyl-5-Trifluoromethyl-1H-Pyridin-2-One is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity and physicochemical properties imparted by the trifluoromethyl group, enabling the development of novel compounds with enhanced metabolic stability and bioavailability. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the CF3 group can improve lipophilicity and biological activity.
• Material Science Research: Serves as a precursor for specialty chemicals and functional materials, including liquid crystals and organic electronic components.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a fluorinated pyridone moiety.

Basic Information

Product Name	1-Methyl-5-Trifluoromethyl-1H-Pyridin-2-One
CAS No.	201160-48-7
Molecular Formula	C7H5F3N2O
Molecular Weight	190.12 g/mol
Synonyms	5-(Trifluoromethyl)-1-methyl-2(1H)-pyridinone; 1-Methyl-5-(trifluoromethyl)pyridin-2(1H)-one; 2-Hydroxy-1-methyl-5-(trifluoromethyl)pyridine; 1-Methyl-5-trifluoromethyl-2-pyridone; 5-Trifluoromethyl-1-methyl-2-pyridone; 1-Methyl-5-trifluoromethyl-1H-pyridin-2-one; 201160-48-7
EINECS	Contact for details

Quality Control

Our production of 1-Methyl-5-Trifluoromethyl-1H-Pyridin-2-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.