Description

Ptp Inhibitor Iii CAS NO 29936-81-0 is a potent and selective small molecule inhibitor of protein tyrosine phosphatase (PTP) enzymes, a critical class of signaling regulators. This compound is essential for researchers and developers in the life sciences sector, enabling precise modulation of cellular signaling pathways for therapeutic discovery and biological mechanism studies. It is primarily utilized in pharmaceutical R&D, academic research, and biotechnology for investigating conditions related to PTP dysregulation, such as metabolic disorders, cancer, and immune diseases.

Application

• Biochemical Research: A key tool for studying the structure, function, and inhibition kinetics of protein tyrosine phosphatases in vitro.
• Drug Discovery & Development: Used as a lead compound or reference standard in high-throughput screening (HTS) campaigns and medicinal chemistry programs targeting PTPs.
• Cellular Signaling Studies: Applied in cell-based assays to elucidate the role of specific PTPs in signal transduction pathways related to growth, differentiation, and apoptosis.
• Target Validation: Serves as a pharmacological probe to validate PTPs as viable therapeutic targets for various diseases.
• Academic & Institutional Research: Fundamental research reagent for universities and research institutes exploring tyrosine phosphorylation dynamics.

Basic Information

Product Name	Ptp Inhibitor Iii
CAS No.	29936-81-0
Molecular Formula	C16H13NO3S
Molecular Weight	299.35 g/mol
Synonyms	PTP Inhibitor III; 2-(Oxalylamino)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid ethyl ester; Ethyl 2-[(oxalyl)amino]-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate; PTP1B Inhibitor; TCPTP Inhibitor; Protein Tyrosine Phosphatase Inhibitor III; NSC 117199
EINECS	Contact for details

Quality Control

Our Ptp Inhibitor Iii is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (NMR, IR, MS) and purity assessment by HPLC. A detailed Certificate of Analysis (COA) providing purity, potency, and analytical data is supplied with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. For short-term use, the material may be stored at 2-8°C. The compound is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.