Description

Ro 20-1724 is a selective and potent inhibitor of phosphodiesterase 4 (PDE4), a key enzyme involved in cellular signaling pathways. This compound is a crucial research tool for studying cyclic AMP (cAMP)-mediated processes, inflammation, and immune cell function. It is primarily utilized by pharmaceutical researchers, academic institutions, and biotechnology companies engaged in drug discovery and basic biochemical research.

Application

• Biochemical Research: A standard tool for investigating the role of PDE4 and cAMP signaling in cellular models.
• Inflammation Studies: Used to modulate inflammatory responses in research related to asthma, COPD, and autoimmune diseases.
• Neuroscience Research: Employed in studies exploring PDE4's role in cognition, memory, and neuropsychiatric disorders.
• Drug Discovery & Screening: Serves as a reference compound or positive control in high-throughput screening assays for novel PDE4 inhibitors.
• Cell Signaling Pathways: Essential for elucidating downstream effects of cAMP elevation in various cell types.

Basic Information

Item	Detail
Product Name	Ro 20-1724
CAS No.	29925-17-5
Molecular Formula	C₁₃H₁₆N₂O₃
Molecular Weight	248.28 g/mol
Synonyms	4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Rolipram analog; PDE4 Inhibitor I; 1-(3-Butoxy-4-methoxyphenyl)methyl]-2-imidazolidinone; 4-[(3-Butoxy-4-methoxyphenyl)methyl]-2-imidazolidinone; Ro-20-1724; Ro 20 1724
EINECS	Contact for details

Quality Control

Our Ro 20-1724 is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.