Description

1-Bromo-3-(Difluoromethyl)Benzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and difluoromethyl substituents, makes it a critical intermediate for introducing specific functionalities into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoromethyl group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated organic compounds for electronic applications, including liquid crystal displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille) to construct complex biaryl systems.
• Functional Material Research: Employed in R&D for creating novel polymers, ligands, and specialty chemicals with tailored properties.

Basic Information

Product Name	1-Bromo-3-(Difluoromethyl)Benzene
CAS No.	29848-59-7
Molecular Formula	C7H5BrF2
Molecular Weight	207.02 g/mol
Synonyms	3-Bromo-α,α-difluorotoluene; m-Bromo-α,α-difluorotoluene; 3-Bromobenzylidene Difluoride; (3-Bromophenyl)difluoromethane; 1-Bromo-3-(difluoromethyl)benzene; 29848-59-7; α,α-Difluoro-3-bromotoluene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(Difluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.