Description

n-Octyl α-D-Glucopyranoside is a high-purity, non-ionic alkyl glycoside surfactant widely used in biochemical and pharmaceutical research. Its primary value lies in its ability to solubilize membrane proteins while maintaining their native structure and function, a critical requirement for structural biology and drug discovery. This product is essential for researchers and manufacturers in biotechnology, pharmaceutical development, and diagnostic kit formulation who require a mild, effective detergent for protein purification and crystallization.

Application

• Membrane Protein Solubilization and Crystallization: A key reagent for extracting and stabilizing integral membrane proteins for structural analysis via X-ray crystallography and cryo-electron microscopy.
• Biochemical Assay Buffer Component: Used in lysis and wash buffers to maintain protein activity in enzymatic assays and receptor-binding studies.
• Pharmaceutical and Vaccine Formulation: Serves as a stabilizing excipient in the development of biologic drugs and vaccines that contain membrane-bound antigens.
• Cell Culture and Microbiology: Employed as a mild detergent for cell lysis and organelle isolation without denaturing sensitive proteins.
• Diagnostic Reagents: Incorporated into buffers for immunoassays and diagnostic test strips to ensure consistent antigen presentation and antibody binding.
• Chromatography: Used in mobile phases for size-exclusion or affinity chromatography of membrane-associated complexes.

Basic Information

Item	Details
Product Name	n-Octyl α-D-Glucopyranoside
CAS No.	29781-80-4
Molecular Formula	C₁₄H₂₈O₆
Molecular Weight	292.37 g/mol
Synonyms	Octyl α-D-Glucopyranoside; α-Octylglucoside; n-Octyl-α-D-glucoside; OGP; Octyl α-D-Glucoside; α-D-Glucopyranoside, octyl; Octylglucoside; 1-Octyl-α-D-glucopyranoside
EINECS	249-861-3

Quality Control

Every batch of our n-Octyl α-D-Glucopyranoside is manufactured under a quality management system and subjected to rigorous analytical testing to ensure it meets the stringent requirements for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our standard grade meets typical specifications for biochemical use, and we can support compliance with relevant guidelines for excipient or reagent use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect purity and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	[α]²⁰D: +80° to +85° (c=1 in H₂O)
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Biological Activity	Passes performance test for protein solubilization

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.