Description

6-Amino-6-Deoxy A-Cyclodextrin is a chemically modified derivative of α-cyclodextrin, featuring a primary amino group at the 6-position of one glucose unit. This functionalization is critical as it introduces a reactive handle for further conjugation, significantly expanding the utility of the native cyclodextrin scaffold. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require advanced molecular encapsulation and targeted delivery systems. Its unique structure enables the creation of sophisticated drug carriers, enzyme mimics, and selective separation media.

Application

• Pharmaceutical Drug Delivery: Serves as a key building block for synthesizing targeted prodrugs and advanced drug delivery systems by conjugating therapeutic agents to the amino group.
• Chiral Separation & Analysis: Used as a chiral selector or stationary phase modifier in High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) for enantiomer resolution.
• Bioconjugation & Immobilization: The primary amine facilitates covalent attachment to proteins, enzymes, or solid supports (e.g., resins, nanoparticles) for creating stabilized biocatalysts or affinity matrices.
• Supramolecular Chemistry Research: Acts as a foundational component for constructing molecular machines, sensors, and complex host-guest assemblies with tailored binding properties.
• Solubility & Stability Enhancement: Forms inclusion complexes to improve the aqueous solubility, bioavailability, and chemical stability of poorly soluble active pharmaceutical ingredients (APIs).
• Catalyst & Ligand Design: Utilized to develop novel asymmetric catalysts or metal-chelating ligands by functionalizing the amino group with specific catalytic moieties.

Basic Information

Item	Detail
Product Name	6-Amino-6-Deoxy A-Cyclodextrin
CAS No.	29556-37-4
Molecular Formula	C36H61NO29
Molecular Weight	947.86 g/mol
Synonyms	6-Amino-6-deoxy-α-cyclodextrin; 6A-Amino-6A-deoxy-α-cyclodextrin; Mono-6-amino-6-deoxy-α-cyclodextrin; 6-Monoamino-β-cyclodextrin (common misnomer); 6-NH2-α-CD; α-Cyclodextrin, 6-amino-6-deoxy-; Heptakis(6-amino-6-deoxy)-α-cyclodextrin (fully substituted derivative, often confused); Amino-α-CD
EINECS	Contact for details

Quality Control

Our 6-Amino-6-Deoxy A-Cyclodextrin is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets rigorous specifications for research and process applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.