Description

4-Chlorophenyl Trifluoromethanesulfonate is a high-purity triflate ester derivative, serving as a versatile and reactive arylating agent in advanced organic synthesis. Its core value lies in enabling efficient carbon-carbon and carbon-heteroatom bond formation, crucial for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of drug candidates, especially in cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to introduce the 4-chlorophenyl moiety.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides where the 4-chlorophenyl group is a critical pharmacophore.
• Material Science Research: Employed in the creation of novel organic electronic materials, ligands for catalysts, and specialty polymers.
• Cross-Coupling Reactions: An excellent electrophile in palladium-catalyzed reactions due to the superior leaving group ability of the triflate anion.
• Chemical Derivatization: Useful for functionalizing complex molecules in medicinal chemistry and process optimization studies.

Basic Information

Product Name	4-Chlorophenyl Trifluoromethanesulfonate
CAS No.	29540-84-9
Molecular Formula	C7H4ClF3O3S
Molecular Weight	260.62 g/mol
Synonyms	4-Chlorophenyl Triflate; 4-Chlorophenyl Trifluoromethanesulphonate; 1-Chloro-4-(trifluoromethanesulfonyloxy)benzene; p-Chlorophenyl Trifluoromethanesulfonate; Trifluoromethanesulfonic Acid 4-Chlorophenyl Ester; 4-Chloro-1-(trifluoromethanesulfonyloxy)benzene; (4-Chlorophenyl) Triflate; 4-Chlorophenyl Trifluoromethylsulfonate
EINECS	Contact for details

Quality Control

Our 4-Chlorophenyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.