Description

6-Monodeoxy-6-Monoamino-β-Cyclodextrine is a chemically modified derivative of β-cyclodextrin featuring a single amino group, which introduces a positively charged, reactive site onto the macrocyclic scaffold. This unique functionalization is critical for creating host-guest complexes with enhanced binding affinity for anionic or hydrophobic guest molecules, enabling precise molecular encapsulation and delivery. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing advanced drug delivery systems, chiral separation media, and supramolecular catalysts.

Application

• Pharmaceutical Drug Delivery: Acts as a functional carrier to improve the solubility, stability, and bioavailability of poorly soluble active pharmaceutical ingredients (APIs).
• Gene Delivery Vectors: Serves as a key component in the synthesis of non-viral vectors for plasmid DNA and siRNA delivery, leveraging its cationic amino group for nucleic acid complexation.
• Chiral Separation & Analysis: Used as a chiral selector or stationary phase modifier in High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) for enantiomer resolution.
• Catalyst & Enzyme Mimics: Forms the basis for constructing artificial enzymes and supramolecular catalysts where the cavity provides a selective reaction environment.
• Sensor Development: Employed in the fabrication of chemical and biosensors, where its selective binding properties are used for analyte recognition and signal transduction.
• Cosmetic & Personal Care: Utilized to stabilize fragrances, vitamins, and other active ingredients in formulations, controlling their release and protecting them from degradation.
• Agrochemical Formulations: Enhances the efficacy and environmental compatibility of pesticides and herbicides by improving their solubility and reducing volatility.

Basic Information

Item	Details
Product Name	6-Monodeoxy-6-Monoamino-β-Cyclodextrine
CAS No.	29390-67-8
Molecular Formula	C42H71NO34
Molecular Weight	1134.00 g/mol (approx.)
Synonyms	6A-Amino-6A-deoxy-β-cyclodextrin; 6-Monoamino-6-monodeoxy-β-cyclodextrin; 6-NH2-β-CD; Mono(6-amino-6-deoxy)-β-cyclodextrin; 6-Deoxy-6-amino-β-cyclodextrin; Heptakis(6-deoxy-6-amino)cyclomaltoheptaose (incorrect for mono-substituted, but a common search variant); 6-Monoamino-β-cyclodextrin; β-Cyclodextrin, 6-amino-6-deoxy-
EINECS	Contact for details

Quality Control

Our 6-Monodeoxy-6-Monoamino-β-Cyclodextrine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and assay, NMR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets high-purity standards suitable for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) documenting all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.