Description

7-[(1R,2S,3R,5R)-3,5-Dihydroxy-2-[(E,3S)-3-Hydroxyoct-1-Enyl]Cyclopentyl]Heptanoic Acid is a high-purity synthetic prostaglandin analog, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and structural complexity, which are critical for biological activity studies. It is primarily utilized by research institutions and pharmaceutical companies focused on developing novel therapeutics in areas such as ophthalmology, cardiovascular medicine, and reproductive health.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and a tool compound in pharmacological studies to investigate prostaglandin receptor activity and signaling pathways.
• Ophthalmic Drug Development: Serves as a precursor in the research and production of drugs for glaucoma and ocular hypertension.
• Cardiovascular Research: Employed in studies exploring vascular tone regulation, platelet aggregation, and inflammatory responses.
• Process Development & Scale-up: Used in method development and optimization for the commercial-scale manufacturing of prostaglandin derivatives.
• Analytical Standard: Provides a high-purity standard for quality control (QC) and analytical method validation (HPLC, LC-MS) in pharmaceutical laboratories.

Basic Information

Product Name	7-[(1R,2S,3R,5R)-3,5-Dihydroxy-2-[(E,3S)-3-Hydroxyoct-1-Enyl]Cyclopentyl]Heptanoic Acid
CAS No.	28977-21-1
Molecular Formula	C20H36O5
Molecular Weight	356.50 g/mol
Synonyms	Latanoprost Acid; Latanoprost Free Acid; 13,14-Dihydro-17-phenyl-18,19,20-trinor-PGF2α; (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid; Prostaglandin F2α analog; 17-Phenyl-18,19,20-trinorprostaglandin F2α; 7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(3S)-3-hydroxy-5-phenyl-1-pentenyl]cyclopentyl]-5-heptenoic Acid
EINECS	Contact for details

Quality Control

Our 7-[(1R,2S,3R,5R)-3,5-Dihydroxy-2-[(E,3S)-3-Hydroxyoct-1-Enyl]Cyclopentyl]Heptanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed container to reach room temperature before opening to minimize condensation and exposure.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.