Description

Clindamycin 3-Phosphate is a water-soluble phosphate ester derivative of the lincosamide antibiotic clindamycin. This prodrug form is specifically designed to enhance solubility and stability for parenteral pharmaceutical formulations. It is a critical active pharmaceutical ingredient (API) and intermediate for manufacturers developing injectable antibiotic treatments. Key industries requiring this compound include pharmaceutical synthesis, biotechnology research, and contract manufacturing organizations (CMOs) producing sterile injectables.

Application

• Primary Active Pharmaceutical Ingredient (API) for the manufacture of sterile injectable clindamycin formulations.
• Key Intermediate in the synthesis of various clindamycin phosphate-based drug products.
• Pharmaceutical Research & Development for studying antibiotic efficacy, pharmacokinetics, and new delivery systems.
• Production of Ready-to-Use Injectables, including vials and pre-filled syringes for hospital use.
• Veterinary Pharmaceutical Applications for developing antibacterial treatments for animals.
• Reference Standard for quality control and analytical testing in pharmaceutical laboratories.

Basic Information

Product Name	Clindamycin 3-Phosphate
CAS No.	28708-34-1
Molecular Formula	C18H34ClN2O8PS
Molecular Weight	504.94 g/mol
Synonyms	Clindamycin Phosphate; Clindamycin 2-Phosphate; 7(S)-Chloro-7-deoxylincomycin 2-phosphate; U-28508; Dalacin C Phosphate; Cleocin Phosphate; Clindamycin Dihydrogen Phosphate; Methyl 7-chloro-6,7,8-trideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate)
EINECS	Contact for details

Quality Control

Our Clindamycin 3-Phosphate is manufactured under strict quality systems to meet the exacting standards of the pharmaceutical industry. Production adheres to current Good Manufacturing Practices (cGMP) guidelines. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring compliance with relevant pharmacopeial monographs (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
pH (Solution)	3.5 - 5.0 (in aqueous solution)
Specific Rotation	+115° to +130° (c=1 in water)
Bacterial Endotoxins	< 0.6 EU/mg (for injectable grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.