Description

4,5-Dihydroxy-4,5-Dihydrobenzo(A)Pyrene is a key dihydrodiol metabolite and synthetic intermediate of the polycyclic aromatic hydrocarbon Benzo(a)pyrene. This compound matters significantly for researchers and industrial chemists as it serves as a crucial reference standard and precursor in the study of metabolic activation pathways, DNA adduct formation, and carcinogenesis. It is primarily needed by the pharmaceutical, toxicology, and environmental analysis sectors for advanced research into chemical carcinogens and the development of analytical methods.

Application

• Metabolic Pathway Research: Used as a critical intermediate in studying the metabolic activation of Benzo(a)pyrene to its ultimate carcinogenic forms.
• Analytical Reference Standard: Serves as a high-purity standard for calibrating equipment (HPLC, GC-MS) in environmental and biological monitoring for PAH exposure.
• Toxicology Studies: Essential for in vitro and in vivo research investigating the mechanisms of PAH-induced toxicity and carcinogenicity.
• Biomarker Development: Utilized in the development and validation of assays to detect specific DNA or protein adducts formed from PAH metabolites.
• Organic Synthesis: Acts as a specialized synthetic building block for creating modified PAH derivatives for structure-activity relationship (SAR) studies.
• Regulatory & Compliance Testing: Supports testing laboratories in meeting regulatory requirements for product safety and environmental contaminant analysis.

Basic Information

Product Name	4,5-Dihydroxy-4,5-Dihydrobenzo(A)Pyrene
CAS No.	28622-84-6
Molecular Formula	C₂₀H₁₄O₂
Molecular Weight	286.32 g/mol
Synonyms	4,5-Dihydro-4,5-dihydroxybenzo[a]pyrene; Benzo[a]pyrene 4,5-dihydrodiol; 4,5-Dihydroxy-4,5-dihydrobenzo[a]pyrene; (+/-)-Benzo[a]pyrene-4,5-dihydrodiol; 4,5-Dihydrobenzo[a]pyrene-4,5-diol; BP-4,5-dihydrodiol; 4,5-Dihydroxy-4,5-dihydro-3,4-benzpyrene
EINECS	Contact for details

Quality Control

Our 4,5-Dihydroxy-4,5-Dihydrobenzo(A)Pyrene is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be kept in secondary opaque packaging or amber glass to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light tan solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content	Contact for details
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.