Description

(3-Beta,14R)-10,20-Didehydro-3,5,14,16-Tetrahydroxygrayanotoxan-6-One CAS NO 28371-51-9 is a high-purity, naturally derived diterpenoid compound belonging to the grayanotoxin family. This specialized chemical is valued for its precise molecular structure and serves as a critical reference standard and advanced research intermediate. It is primarily sought by research institutions and pharmaceutical development companies engaged in neurobiological studies, ion channel research, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in drug development.
• Neuroscience Research: Serves as a key tool compound for studying voltage-gated sodium channels, aiding in the investigation of neurological pathways and mechanisms.
• Toxicology Studies: Employed as a precise analytical standard in forensic and environmental toxicology for the identification and quantification of grayanotoxin-related substances.
• Natural Product Synthesis: Acts as a sophisticated chiral building block or intermediate for the semi-synthesis of complex natural products and potential drug candidates.
• Academic Research: Utilized in university and institutional labs for chemical, pharmacological, and biological research pertaining to diterpenoid chemistry.
• Biochemical Assay Development: Provides a high-purity ligand for developing and calibrating in vitro assays targeting specific receptor interactions.

Basic Information

Product Name	(3-Beta,14R)-10,20-Didehydro-3,5,14,16-Tetrahydroxygrayanotoxan-6-One
CAS No.	28371-51-9
Molecular Formula	C20H30O6
Molecular Weight	366.45 g/mol
Synonyms	Grayanotoxin III; Acetylandromedol; 14-Hydroxygrayanotoxin II; Andromedotoxin; Grayanotoxin-3; Rhodojaponin III; (3β,6β,14R)-Grayane-3,5,6,10,14,16-hexaol-6-acetate; 28371-51-9
EINECS	Contact for details

Quality Control

Our (3-Beta,14R)-10,20-Didehydro-3,5,14,16-Tetrahydroxygrayanotoxan-6-One is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods, and impurity profiles. We adhere to relevant industry standards for analytical reference materials to support your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.