Description

2,4-Dichloro-5-Methylbenzenesulfonyl Chloride is a key sulfonyl chloride intermediate prized for its high reactivity in introducing the sulfonamide functional group. This compound matters for its role in synthesizing complex molecules with tailored biological and chemical properties. It is primarily needed by pharmaceutical, agrochemical, and specialty chemical manufacturers for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of sulfonamide-based drugs, including diuretics, anti-bacterials, and protease inhibitors.
• Agrochemical Synthesis: Used in the production of modern herbicides, fungicides, and pesticides, leveraging its dichloro-methyl substituted aromatic structure.
• Dyestuff and Pigment Manufacturing: Serves as a precursor for sulfonated dyes and pigments, enhancing color fastness and solubility.
• Polymer Modification: Employed to introduce sulfonyl chloride groups into polymer chains for subsequent functionalization, creating ion-exchange resins or specialty polymers.
• Chemical Research & Development: A valuable reagent in organic synthesis for constructing complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	2,4-Dichloro-5-Methylbenzenesulfonyl Chloride
CAS No.	28286-86-4
Molecular Formula	C7H5Cl3O2S
Molecular Weight	259.54 g/mol
Synonyms	5-Methyl-2,4-dichlorobenzenesulfonyl chloride; 2,4-Dichloro-5-methylbenzene-1-sulfonyl chloride; 2,4-Dichloro-5-methylphenylsulfonyl chloride; 2,4-Dichloro-α,α,α-trifluoro-m-toluenesulfonyl chloride (related compound check); Benzenesulfonyl chloride, 2,4-dichloro-5-methyl-; 2,4-Dichloro-5-methylbenzenesulphonyl chloride; 2,4-Dichloro-5-methyl-benzolsulfonylchlorid
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Methylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets exacting standards for use in sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or lumps
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.