Description

1,1-Dimethylpropylmagnesium Chloride is a highly reactive organomagnesium compound, commonly known as a Grignard reagent. This chemical is a critical building block in organic synthesis, valued for its ability to introduce the bulky tert-pentyl group into target molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise carbon-carbon bond formation for creating complex intermediates and active ingredients.

Application

• As a key nucleophile in Grignard reactions for the synthesis of tertiary alcohols, ketones, and carboxylic acids.
• Production of pharmaceutical intermediates, particularly for compounds requiring sterically hindered alkyl groups.
• Manufacture of agrochemicals, including pesticides and herbicides, where the tert-pentyl moiety imparts specific biological activity.
• Synthesis of fine chemicals and specialty materials used in flavors, fragrances, and electronic chemicals.
• As a reagent in polymer chemistry for initiating anionic polymerizations or modifying polymer chains.
• Laboratory-scale organic research for method development and exploring new synthetic pathways.

Basic Information

Product Name	1,1-Dimethylpropylmagnesium Chloride
CAS No.	28276-08-6
Molecular Formula	C5H11ClMg
Molecular Weight	130.90 g/mol
Synonyms	tert-Pentylmagnesium Chloride; (1,1-Dimethylpropyl)magnesium Chloride; Neopentylmagnesium Chloride (common misnomer); 2-Methyl-2-butylmagnesium Chloride; 1,1-Dimethylpropylmagnesium Chloride solution; Grignard Reagent (tert-pentyl); t-Amylmagnesium Chloride; Magnesium, chloro(1,1-dimethylpropyl)-
EINECS	Contact for details

Quality Control

Our 1,1-Dimethylpropylmagnesium Chloride is produced and handled under stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analysis, including titration for assay and impurity profiling. A Certificate of Analysis (COA) detailing purity, concentration, and solvent content is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this product must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for extended stability. Keep away from moisture, heat, and incompatible materials such as strong acids, oxidizing agents, and protic solvents.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration (in specified solvent)	Typically 0.5M to 2.0M in THF or Diethyl Ether
Assay (by Titration)	≥ 95% (as Grignard reagent)
Identification (IR/NMR)	Conforms to structure
Solvent Content	Balance

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.