Description

Naphthyl Glucuronide CAS NO 27710-10-7 is a high-purity biochemical conjugate of naphthol and glucuronic acid, serving as a critical reference standard and intermediate. Its primary value lies in enabling precise analytical quantification and metabolic pathway studies in research and development. This compound is essential for pharmaceutical R&D laboratories, diagnostic kit manufacturers, and academic institutions focused on enzymology and toxicology.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (HPLC, LC-MS) in drug metabolism and pharmacokinetics (DMPK) studies.
• Enzyme Substrate: Acts as a specific substrate for β-glucuronidase enzyme activity assays in clinical diagnostics and biochemical research.
• Biomarker Research: Employed in the study of phase II drug metabolism and the detection of specific glucuronide conjugates as exposure biomarkers.
• Diagnostic Reagent Manufacturing: A key raw material in the production of reagents for enzymatic diagnostic tests and kits.
• Toxicology Studies: Used to investigate detoxification pathways and the formation of glucuronide metabolites of various xenobiotics.
• Academic & Industrial R&D: Serves as a crucial tool in fundamental research on conjugation reactions and enzyme mechanisms.

Basic Information

Product Name	Naphthyl Glucuronide
CAS No.	27710-10-7
Molecular Formula	C₁₆H₁₈O₈
Molecular Weight	338.31 g/mol
Synonyms	1-Naphthyl β-D-Glucopyranosiduronic Acid; 1-Naphthol Glucuronide; α-Naphthyl Glucuronide; Naphthol-β-D-glucuronide; Glucuronic Acid 1-Naphthyl Ester; β-1-Naphthylglucuronide; 1-Naphthyl-β-D-glucuronide
EINECS	Contact for details

Quality Control

Our Naphthyl Glucuronide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for use as a reference material. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.