Description

2,3-Dihydro-2-Oxobenzoxazole-6-Sulphonyl Chloride is a high-purity, reactive chemical intermediate featuring a benzoxazolone core activated by a sulfonyl chloride group. This compound matters for its role as a key building block in the synthesis of more complex molecules, enabling the introduction of the sulfonamide moiety. It is primarily needed by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the sulfonamide group confers specific biological activity.
• Dye and Pigment Manufacturing: Serves as a reactive intermediate for creating sulfonated dyes and specialty colorants with enhanced properties.
• Polymer Modification: Employed to introduce sulfonamide functional groups into polymer chains, altering characteristics like solubility or biocompatibility.
• Chemical Research & Development: A versatile reagent for organic synthesis, particularly in medicinal chemistry for constructing diverse compound libraries.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands for metal complexes or functionalized catalysts.

Basic Information

Product Name	2,3-Dihydro-2-Oxobenzoxazole-6-Sulphonyl Chloride
CAS No.	27685-90-1
Molecular Formula	C7H4ClNO4S
Molecular Weight	233.63 g/mol
Synonyms	6-(Chlorosulfonyl)-2(3H)-benzoxazolone; 2-Oxo-2,3-dihydrobenzoxazole-6-sulfonyl chloride; 2,3-Dihydro-2-oxo-1,3-benzoxazole-6-sulfonyl chloride; Benzoxazolone-6-sulfonyl chloride; 6-Chlorosulfonyl-2-benzoxazolinone; 2-Hydroxybenzoxazole-6-sulfonyl chloride; 2-Benzoxazolinone-6-sulfonyl chloride; 1,3-Benzoxazol-2(3H)-one, 6-(chlorosulfonyl)-
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-2-Oxobenzoxazole-6-Sulphonyl Chloride is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.