Description

Equilin 3-o-β-D-Glucuronide Sodium Salt is a high-purity conjugated metabolite of the equine estrogen equilin, specifically the sodium salt of its 3-O-glucuronide derivative. This compound is of significant value as a critical reference standard and analytical reagent for the precise quantification and metabolic profiling of equilin in biological matrices. It is primarily required by pharmaceutical R&D laboratories, clinical research organizations, and diagnostic manufacturers focused on hormone analysis, pharmacokinetic studies, and the development of bioanalytical assays.

Application

• Pharmaceutical Reference Standard: Used as a primary standard for the calibration of HPLC, LC-MS, and GC-MS systems in the analysis of equilin and its metabolites.
• Metabolite Research: Essential for studying the Phase II glucuronidation pathway and pharmacokinetics of equine estrogens in preclinical and clinical research.
• Bioanalytical Method Development: Serves as a key component in developing and validating sensitive and specific assays for hormone levels in serum, plasma, and urine.
• Quality Control in API Manufacturing: Employed in the quality control of conjugated estrogen active pharmaceutical ingredients (APIs) to monitor specific metabolite content.
• Diagnostic Kit Production: Utilized as a calibrator or control in the manufacture of in-vitro diagnostic (IVD) kits for endocrine testing.
• Academic Research: Used in university and institutional research investigating steroid hormone metabolism, receptor interactions, and related biochemical pathways.

Basic Information

Product Name	Equilin 3-o-β-D-Glucuronide Sodium Salt
CAS No.	27610-12-4
Molecular Formula	C25H31O9Na
Molecular Weight	498.5 g/mol
Synonyms	Equilin 3-Glucuronide Sodium Salt; Sodium Equilin 3-Glucuronide; 3-Hydroxyequilin 3-Glucuronide Sodium Salt; 3-Glucuronosylequilin Sodium Salt; Equilin 3-O-β-D-Glucopyranosiduronic Acid Sodium Salt; NSC 147079; Estr-1,3,5(10),6,8-pentaen-3-ol-17-one 3-(β-D-glucopyranosiduronic acid) Sodium Salt
EINECS	Contact for details

Quality Control

Our Equilin 3-o-β-D-Glucuronide Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Assay (HPLC)	95.0% - 105.0%
Water Content (KF)	≤5.0%
Residue on Ignition	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.