Description

Lincomycin 2-Phosphate is a semi-synthetic, water-soluble phosphate ester derivative of the lincosamide antibiotic lincomycin. This chemical modification enhances its stability and solubility, making it a critical intermediate in the synthesis of advanced pharmaceutical formulations. It is primarily utilized by manufacturers in the pharmaceutical and veterinary medicine industries for the development of injectable antibiotic treatments. The compound is supplied under stringent quality controls to ensure consistency for research and production-scale applications.

Application

• Pharmaceutical Intermediate: Key starting material in the synthesis of clindamycin phosphate and other advanced lincosamide antibiotics.
• Veterinary Medicine Production: Used in formulating injectable antibiotic solutions for treating bacterial infections in livestock and companion animals.
• Antibiotic Research: Serves as a reference standard and building block in microbiological and pharmacological R&D for novel antimicrobial agents.
• API Manufacturing: Critical intermediate in the cGMP production of Active Pharmaceutical Ingredients (APIs) for human and veterinary use.
• Laboratory Reagent: Used as a high-purity biochemical reagent in academic and industrial research laboratories.

Basic Information

Product Name	Lincomycin 2-Phosphate
CAS No.	27480-30-4
Molecular Formula	C18H34N2O8PS
Molecular Weight	469.50 g/mol
Synonyms	Lincomycin Phosphate; Lincomycin 2-(Dihydrogen Phosphate); Lincomycin 2-Phosphate Salt; U-10149A; Antibiotic U-10149A; Methyl 6,8-Dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside 2-(Dihydrogen Phosphate); (2S,4R)-N-[(1R,2R)-2-Hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide 2-(Dihydrogen Phosphate)
EINECS	Contact for details

Quality Control

Our Lincomycin 2-Phosphate is manufactured and tested under a quality management system. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical intermediate use. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.