Description

2-(3-Fluoro-Phenyl)-1H-Imidazole is a versatile fluorinated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the imidazole core combined with the electronic effects of the fluorophenyl substituent, enabling precise molecular design. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced fungicides and herbicides, where the fluorine atom enhances bioavailability and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for N-heterocyclic carbene (NHC) ligands and other organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with tailored thermal and electronic properties.
• Chemical Biology Probes: Utilized in the design of fluorescent tags and molecular probes for studying biological processes.

Basic Information

Product Name	2-(3-Fluoro-Phenyl)-1H-Imidazole
CAS No.	27423-79-6
Molecular Formula	C9H7FN2
Molecular Weight	162.16 g/mol
Synonyms	2-(3-Fluorophenyl)-1H-imidazole; 1H-Imidazole, 2-(3-fluorophenyl)-; 3-Fluorophenylimidazole; 2-(m-Fluorophenyl)imidazole; 27423-79-6; 2-(3-Fluorophenyl)imidazole; NSC 405124; AI3-52099
EINECS	Contact for details

Quality Control

Our 2-(3-Fluoro-Phenyl)-1H-Imidazole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment, and we support custom purity requirements for research and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.