Description

Antimycin A2 is a specific, high-purity congener of the Antimycin A complex, a potent inhibitor of mitochondrial electron transport. This compound is valued for its precise biological activity, making it a critical tool for research in biochemistry and cell biology. It is primarily utilized by researchers in the life sciences, pharmaceutical development, and agrochemical sectors for studying cellular respiration, apoptosis, and as a reference standard.

Application

• Biochemical Research: As a specific inhibitor of the mitochondrial electron transport chain (complex III), used to study cellular respiration, ATP production, and oxidative phosphorylation.
• Apoptosis Studies: Employed to induce programmed cell death in research models to investigate apoptotic pathways and mechanisms.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in drug discovery and development labs.
• Agrochemical Research: Investigated for its potential as a lead compound or mode-of-action reference in the development of novel fungicides or insecticides.
• Metabolic Pathway Analysis: Used in cancer research and metabolic disease studies to probe the role of mitochondrial function in disease progression.

Basic Information

Product Name	Antimycin A2
CAS No.	27220-57-1
Molecular Formula	C26H38N2O9
Molecular Weight	522.59 g/mol
Synonyms	Antimycin A2; Antimycin A II; NSC 107412; Antibiotic A2; 3-Formamido-2-hydroxybenzoyl-L-threonyl-D-alloisoleucyl-L-valine lactone (3'-methylbutyrate); 3-Formamidosalicyloyl-L-threonyl-D-alloisoleucyl-L-valine lactone (3'-methylbutyrate)
EINECS	Contact for details

Quality Control

Our Antimycin A2 is produced and tested under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant standards for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere to minimize oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.