Description

4-Ethylbenzotrifluoride is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an ethyl group and a trifluoromethyl substituent on the benzene ring, makes it a key intermediate for introducing lipophilic and electron-withdrawing properties into target molecules. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethylated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve pesticidal activity and environmental profile.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), contributing to desired electronic and physical properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter characteristics such as chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and other transformations to construct complex, fluorinated molecular architectures for research and development.
• Dye & Pigment Intermediate: Utilized in the production of specialized dyes and pigments where fluorine substitution can affect color fastness and solubility.

Basic Information

Product Name	4-Ethylbenzotrifluoride
CAS No.	27190-69-8
Molecular Formula	C9H9F3
Molecular Weight	174.16 g/mol
Synonyms	1-Ethyl-4-(trifluoromethyl)benzene; p-Ethylbenzotrifluoride; p-Ethyl-α,α,α-trifluorotoluene; 4-Ethyl-α,α,α-trifluorotoluene; 4-Ethylbenzylidyne trifluoride; (4-Ethylphenyl)trifluoromethane; 4-Ethyl-α,α,α-trifluoromethylbenzene; 4-ETF
EINECS	Contact for details

Quality Control

Our 4-Ethylbenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting key parameters such as assay and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Refractive Index (n20D)	1.450 - 1.455
Density (20°C)	1.18 - 1.22 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.