Description

4,5,6-Trifluoro-2-Trifluoromethyl-Pyrimidine is a highly fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its value lies in its unique structure, which introduces multiple fluorine atoms and a reactive pyrimidine core into target molecules, enabling the fine-tuning of electronic properties, lipophilicity, and metabolic stability. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated active pharmaceutical ingredients (APIs), particularly in oncology, antiviral, and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where fluorine substitution enhances biological activity and environmental persistence.
• Material Science Precursor: Serves as a building block for fluorinated polymers, liquid crystals, and electronic materials requiring specific dielectric properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, nucleophilic substitutions, and as a scaffold for constructing complex heterocyclic systems in medicinal chemistry.
• Fluorine Chemistry Research: An important compound for academic and industrial research focused on the synthesis and properties of perfluorinated heteroaromatics.

Basic Information

Item	Detail
Product Name	4,5,6-Trifluoro-2-Trifluoromethyl-Pyrimidine
CAS No.	27077-33-4
Molecular Formula	C5HF6N2
Molecular Weight	194.06 g/mol
Synonyms	2-(Trifluoromethyl)-4,5,6-trifluoropyrimidine; 4,5,6-Trifluoro-2-(trifluoromethyl)pyrimidine; Perfluoromethylpyrimidine; Pyrimidine, 4,5,6-trifluoro-2-(trifluoromethyl)-; 27077-33-4; 4,5,6-Trifluoro-2-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 4,5,6-Trifluoro-2-Trifluoromethyl-Pyrimidine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, keep away from heat, sparks, and open flame. Ensure containers are kept tightly sealed to prevent evaporation and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.